Resume - Esther van de Vosse


PhD in Molecular Genetics, 1991-1997 

Department of Human Genetics, Leiden University, the Netherlands


MSc in Biomedical Sciences, 1985-1991   

Medical Faculty, Leiden University, The Netherlands


Science Consultant, Medical Writer, since February 2018

Owner at EV Science Consultant.

Assistant Professor,  September 2006 – August 2017

Department of Infectious DiseasesLeiden University Medical Center,  the Netherlands

Main interest: immunology and genetics of (myco)bacterial infections.

● Clinical research focus:

–  Identification of genetic defects in patients with the immunodeficiency Mendelian susceptibility to mycobacterial disease (MSMD).

–  Development of therapeutic strategies to treat MSMD patients.

● Basic research focus:

–  Development of in vitro expression models to study the effects of variations and mutations in the IL-12/IFN-gamma signaling pathways
–   Study the IL-12/IFN-gamma signaling pathways and the cell types involved (in healthy individuals)
–   Identify genes and molecules involved in host susceptibility to (bacterial) infections.


Post-doc researcher, September 2001 – August 2006

Dept of Infectious Diseases and the Dept of Immunohematology & Blood transfusion, Leiden University Medical Center, The Netherlands

Subject: Genetic basis of susceptibility to disease and disease-manifestations of infections caused by intracellular bacterial pathogens.

Post-doc researcher, February 1998 – August 2001

Department of Molecular, Cellular and Developmental Biology, the University of Colorado at Boulder, United States

Project funded by the Howard Hughes Medical Institute and UC Boulder

Subject: Identification of Drosophila melanogaster genes involved in axis formation during oogenesis.